भाकृअनप - राष्ट्रीय पशुरोग जानपदिक एवं सूचना विज्ञान संस्थान
ICAR - National Institute Of Veterinary Epidemiology and Disease Informatics
Post Box no: 6450, Yelahanka, Bengaluru, 560064

Home ACHIEVEMENTS AT NIVEDI

SCIENTIFIC ACHIEVEMENTS
1.National Animal Disease Referral Expert System (NADRES) - web based dynamic and interactive livestock disease relational database supported by Geographic Information System (GIS) and includes the disease forecasting modules - www.nadres.res.in.
2.The NADRES was shifted to MySQL platform and linked to ERNET service provider with a web address as www.nadres.res.in.
3.The NADRES software was updated and the data of 609 districts of the country was linked to GIS software.
4.Updated pathozones and ecopathozones of major livestock diseases were plotted and uploaded on to the NADRES.
5.The livestock disease forecast data has been updated with the latest values for the parameters involved for each disease.
6.Spatial distribution of the diseases have been analysed and the diseases have been re-mapped based on their relative occurrence.
7.EpiInfo© software of CDC Atlanta, USA has been optimized to suit the needs to study veterinary epidemiology in the country. Further, veterinarians have been trained for the use of the software for epidemiological analysis.
8.Sampling frame for epidemiological investigation of livestock diseases.
9.Software for estimation of sample size for epidemiological studies on Livestock diseases.
10.MS Access based Software for National Livestock Serum Repository developed.
11.Eco-pathozones for the economically important livestock diseases identified.
12.Bluetongue disease map for Karnataka and Tamil Nadu state developed. GIS based disease mapping of bluetongue initiated.
13.Seroprevalence of Brucellosis, Infectious Bovine Rhinotracheitis, Peste des petitis ruminants (PPR) and Neosporosis (Neospora caninum) in animals in the country.
14.Development of ELISA for the detection of antibodies against Brucella abortus in cattle, B. melitensis in sheep and goat, B. suis in pigs and a common conjugate ELISA for detection of anti-Brucella antibodies in various species of animals and humans.
15.PCR protocols have been optimized for detecting Brucella organisms and differentiating various Brucella species.
16.Genome Sequencing of Brucella melitensis ADMAS-G1, isolated from placental fluids of aborted goat (1st time in India- Whole genome sequencing of Brucella melitensis)
17.Prevalence of Leptospira intermediate species in man and animals in India identified.
18.Seroprevalence of Leptospira intermediate species serovars in livestock in India identified.
19.Multiplex PCR for identification and detection of pathogenic and non-pathogenic Leptospira organisms was standardized.
20.Extensive and in depth study on epidemiology of mastitis is undertaken with special reference to local and global epidemiology of pathogens and the factors associated in causation of mastitis (under NAIP lead project). A total of 205 organisms were isolated based on colony morphology and other cultural characteristics and identified by genus and species specific PCR/mPCR assay standardized earlier.
21.Molecular epidemiology of Staphylococcus revealed that none of the S.aureus isolates belonged to ST 398 which is an important factor in zoonosis.
22.A quantitative multiplex PCR was standardized for detection of 14 mastitis pathogens.
23.Coagulase negative staphylococci (CoNS) identified as emerging pathogen in bovine subclinical mastitis.
24.S. aureus spa (staphylococcal protein A) type t267 found to be the major ancestral clone associated with bovine mastitis in India.
25.Very low methicillin resistance in livestock associated Staphylococcus aureus recognized.
26.Very low prevalence of extended spectrum beta lactamase (ESBL) producer among E. coli from animals.
27.Developed mouse mastitis model to understand host pathogen interaction in bovine mastitis
28.Phylogenetic tree of Indian isolates of CSF was plotted. The study revealed existence of at least two genetic subgroups (1.1 and 2.1) of CSF virus in India.
29.The molecular epidemiology studies of Bovine herpes virus-1 showed that all the Indian strains that were studied belong to subtype 1.1
30.PCR to detect carrier animals of Trypanosomiasis capable of detecting 0.5 tryps/ml.
31.A sero-prevalence study on Caprine Neosporosis was conducted among 3975 randomly selected healthy goats from 9 states within four different geographical regions of the country by employing c-ELISA. Over all 7.93% goats were found to be positive for the presence of Neospora caninum antibodies.
32.A multiplex PCR was developed for identification of E. coli simultaneously differentiating from Shigella sp. and other members of Enterobacteriaceae family. A multiplex PCR (two tube format) was developed for sensitive, specific and simultaneous detection of 10 mastitic pathogens
33.Multiplex PCR for the simultaneous detection of five most prevalent Staphylococcal species was developed.
34.NIVEDI is one of the twelve centres which have been actively working on zoonotic diseases under Outreach Programme on Zoonotic Diseases (OPZD) by Indian Council of Agricultural Research since November, 2009. Under the outreach programme on zoonotic diseases, epidemiology of brucellosis, leptospirosis and listeriosis in addition to their zoonotic relevance studied.
35.The cataloguing process of the national livestock serum bank has been streamlined with alphanumeric labelling of each sample received at the Bank and assigning a barcode. A system has been introduced to collect the serum from various parts of the country based on stratified random sampling method.
36.The institute provided the sampling frame for the FMD-CP, AINP on BT and PPR-CP.
37.Through various training programmes NIVEDI has been able to make an impact on the performance of scientists and professional development due to new knowledge gained and the skills acquired by them.
TECHNOLOGIES DEVELOPED
1.Animal Health Information System for disease monitoring and surveillance in India
2.Weather Based Animal Disease Forecasting - two months in advance for fifteen economically important diseases -www.nadres.res.in.
3.India.admas Epitrak– Exclusive epidemiology offline software.
4.Training modules for research methodology, epidemiology and biostatistics.
5.Avidin-Biotin ELISA Kits for detection of antibodies against Bovine Brucellosis and Infectious Bovine Rhinotracheitis.
6.Indirect ELISA kit for serodiagnosis of sheep and goat brucellosis.
7.Recombinant protein-G based common indirect ELISA kit for serodiagnosis of brucellosis in man and animals.
8.Recombinant Variable Surface Glycoprotein (VSG) based indirect ELISA for sero-surveillance of Trypanosoma evansi infection (Surra) in bovines.
9.Silver staining kit for diagnosis of leptospirosis.
10.PCR assay for detection of bovine herpes virus -1 (BoHV-1) infection in bovine semen.
11.RT-PCR assay for detection of Classical Swine Fever Virus infection in pigs.
12.Multiplex PCR assay for speciation of Brucella isolates from man and animal.
13.Multiplex PCR for identifying 10 major mastitis pathogens, Staphylococcus spp. (5) and Streptococcus spp. (3) in mastitis.
14.Multiplex PCR for identification of E. coli differentiating from Shigella spp. and Klebsiella spp.
15.PCR assay to detect carrier status of Surra in animals.

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